THE SCIENCE

Physiological Effects — How This Pre-Workout Works at a Science Level

1. Pump & Blood Flow Enhancers

What it Does Scientifically L-Citrulline (6g) Converts to L-arginine in the kidneys → increases Nitric Oxide (NO) production → vasodilation → more blood flow to muscles → bigger pumps, more oxygen & nutrient delivery. Citrulline is better absorbed than taking arginine directly. L-Arginine (2g) Immediate substrate for Nitric Oxide Synthase (NOS) → increases NO but is less bioavailable due to liver metabolism; combined with citrulline increases plasma arginine levels synergistically. Pine Bark Extract (100mg, 95% Proanthocyanidins) Boosts endothelial nitric oxide synthase (eNOS) → stabilizes NO → enhances vasodilation & blood flow. Also antioxidant → reduces oxidative stress during training. Grape Seed Extract (100mg, 10:1) High in oligomeric proanthocyanidins (OPCs) → protects nitric oxide from breakdown by free radicals → prolongs muscle pump & vascular relaxation. Pomegranate Extract (500mg, 40% Ellagic Acid) Increases mitochondrial function, reduces inflammation, has nitrate-like NO boosting effects. Improves blood vessel dilation + oxygen efficiency during endurance exercise.

2. ATP Production & Strength Output

Mechanism Betaine Anhydrous (TMG) (3g) Donates methyl groups → supports creatine synthesis in liver. Also improves cellular hydration → increases muscle force production & power output. Taurine (1g) Regulates calcium signaling inside muscle cells → enhances muscular contractions. Improves cell hydration & protects mitochondria from oxidative stress. Dextrose (1g) Fast carbohydrate → increases blood glucose → boosts insulin slightly → helps shuttle amino acids and citrulline into muscle faster. Provides immediate ATP substrate for explosive sets. Sodium (117mg Pink Himalayan Salt) Critical for nerve impulse transmission & muscle contraction. Also regulates fluid balance, improves pump by drawing water into muscle cells (cell volumization).

3. Focus, Mental Drive & Stress Resistance

Brain Science Rhodiola Rosea (200mg) Increases dopamine & serotonin levels while reducing cortisol. Supports AMPK (energy sensor enzyme) → better endurance, mental clarity & reduced fatigue perception. AstraGin® (50mg — Panax Ginseng + Astragalus) Increases absorption of amino acids (like citrulline, arginine, beta-alanine) via upregulation of intestinal transporters (SGLT1, CAT1, PEPT1). Also helps stabilize blood sugar & improve gut health. Taurine (again) Acts on GABA receptors in the brain → anxiolytic (anti-anxiety) effects → cleaner focus without jittery caffeine-like crash. Rhodiola + Pomegranate combo Improves cerebral blood flow & reduces neural fatigue → helps mentally push harder during sets.

4. Anti-Fatigue, Muscle Protection & Recovery

Biological Impact Citrulline Reduces ammonia buildup → delays muscle fatigue from high-intensity sets. Betaine Prevents homocysteine buildup → protects cardiovascular system & improves protein synthesis. Rhodiola Activates AMPK pathway → improves oxygen efficiency → reduces lactate accumulation. Pomegranate / Grape Seed / Pine Bark Fight oxidative stress (ROS) generated during lifting → protect mitochondria & muscle cells. Taurine Prevents muscle cell damage by stabilizing membranes and reducing calcium overload.

💥 In Summary — You Take This, Your Body Does:


  • Increases nitric oxide → bigger pumps & vascularity

  • Produces more ATP & creatine → more reps & power

  • Enhances oxygen use → less fatigue, more endurance

  • Boosts neurotransmitter balance → clean mental focus

  • Shields muscles & mitochondria from oxidative stress

  • Improves nutrient absorption → more effective dose delivery